Collapsed at the kitchen sink with no warning, out for a few seconds
The case
77-year-old woman. Collapsed at the kitchen sink with no warning, out for a few seconds
Paroxysmal atrial fibrillation on apixaban. Treated hypertension. Bisoprolol increased from 2.5 mg to 5 mg three weeks ago for palpitations. Two similar collapses in the past month, both unwitnessed.
On arrival
HR
46
SpO₂ (%)
97
Respiratory rate
16
Temperature (°C)
36.4
Systolic BP (mmHg)
122
Diastolic BP (mmHg)
70
Stage 1 of 2
She is alert, warm and dry, with no injuries from the fall and no tongue biting or incontinence. Heart sounds are normal and there is no murmur. On the monitor she goes pale mid-sentence, is unresponsive for a few seconds, then comes round on her own with no intervention. This is the strip across that moment.
She is back to herself and remembers none of it. Potassium 4.2, magnesium 0.85, TSH normal, creatinine 84, troponin not raised. She has been anticoagulated for three years and has never missed a dose. She asks whether she can go home, and whether the tablets are to blame.
Bloods
TSH (m IU/L)
2.1
Magnesium (mmol/L)
0.85
Potassium (mmol/L)
4.2
Creatinine (umol/L)
84
Diagnosis
Tachy-brady sick sinus syndrome: an asystolic conversion pause on termination of atrial fibrillation
This strip captures a conversion pause: atrial fibrillation terminates and the sinus node, suppressed by the preceding tachycardia, takes several seconds to recover. The pause is long enough to cause syncope. The recent increase in bisoprolol is a likely contributor, both to the sinus suppression and to the slow rate on recovery, so reducing or stopping it is the first step.
A witnessed asystolic pause of this length with syncope is an indication for pacemaker implantation, and the discussion should happen during this admission. A Holter alone risks missing infrequent pauses, and the strip already shows what it would be looking for.
References
Brignole M, Moya A, de Lange FJ, et al. 2018 ESC Guidelines for the diagnosis and management of syncope. Eur Heart J. 2018;39(21):1883-1948.
Kusumoto FM, Schoenfeld MH, Barrett C, et al. 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay. J Am Coll Cardiol. 2019;74(7):e51-e156.
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